Immunomodulatory Effects Mediated by Serotonin
نویسندگان
چکیده
منابع مشابه
Immunomodulatory Effects Mediated by Serotonin
Serotonin (5-HT) induces concentration-dependent metabolic effects in diverse cell types, including neurons, entherochromaffin cells, adipocytes, pancreatic beta-cells, fibroblasts, smooth muscle cells, epithelial cells, and leukocytes. Three classes of genes regulating 5-HT function are constitutively expressed or induced in these cells: (a) membrane proteins that regulate the response to 5-HT...
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Dopamine (DA), a neurotransmitter in the central nervous system (CNS), has modulatory functions at the systemic level. The peripheral and central nervous systems have independent dopaminergic system (DAS) that share mechanisms and molecular machinery. In the past century, experimental evidence has accumulated on the proteins knowledge that is involved in the synthesis, reuptake, and transportat...
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There is a strong consensus that nutrition plays a role in modulating immune function and that the immune system needs adequate supply of nutrients to function properly. The complexity of the immune system supports this idea because its optimal functioning involves a variety of biological activities including cell division and proliferation, energy metabolism, and production of proteins. The mi...
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It is well known that radiotherapy, as mainly locoregional treatment, has systemic eff ects as well. The term abscopal eff ect (latin: ab – away from; scopus – target) has been used to describe the regression of distant tumor metastases after completion of primary tumor radiation therapy. It has been shown that radiotherapy can initiate systemic antitumor immunologic response which includes the...
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Background: Plant extracts have been widely investigated for possible immunomodu-latory properties. Objective: To study the immunomodulatory functions of the metha-nol extract of Haussknechtia elymatica (Apioideae), an herb native to south-western Iran. Methods: Delayed type hypersensitivity (DTH) skin test and measurement of an-tibody titer after immunization with Sheep-RBC was performed. [3H]...
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ژورنال
عنوان ژورنال: Journal of Immunology Research
سال: 2015
ISSN: 2314-8861,2314-7156
DOI: 10.1155/2015/354957